Isosorbide Dicaprylate
Brief Description
Isosorbide Dicaprylate is an ester derived from isosorbide, a sugar alcohol, and caprylic acid, a medium-chain fatty acid. It functions as a skin-conditioning agent, enhancing hydration and improving the skin's barrier function. Its emollient properties contribute to a smooth, non-greasy feel in cosmetic formulations.
INCI Name
Isosorbide Dicaprylate
Appearance
Clear, colorless to pale yellow liquid with a mild odor.
Formulation Guidance
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How to Formulate:
- Incorporate into the oil phase of emulsions.
- Compatible with a wide range of cosmetic ingredients.
- Stable under typical formulation conditions.
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Usage Rate:
- Commonly used at concentrations of 1–10%, depending on the desired emolliency and formulation type.
Scientific Data on Efficacy
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Benefits:
- Acts as a skin-conditioning agent, imparting a soft, smooth feel.
- Enhances the spreadability of formulations.
- Contributes to the stability and viscosity of emulsions.
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Research and Studies:
- A study published in the International Journal of Cosmetic Science demonstrated that Isosorbide Dicaprylate significantly improves skin hydration and enhances the epidermal barrier function.
- Research highlighted in Cosmetics & Toiletries indicates its role in modulating biochemical pathways linked to water and barrier homeostasis, contributing to improved skin moisturization.
pH Stability Range
Stable across a broad pH range, typically 4–8, making it suitable for various cosmetic formulations.
Solubility
Soluble in oils and organic solvents; insoluble in water.
Why Use It in Formulations
Isosorbide Dicaprylate offers multiple benefits:
- Provides a non-greasy, silky feel to the skin.
- Enhances the stability and viscosity of emulsions.
- Improves the solubility and delivery of active ingredients.
Stability Considerations
The ingredient is stable under standard storage conditions but should be kept away from high heat and direct sunlight to maintain efficacy. Proper storage ensures long-term functionality in formulations.
Possible Alternatives
- Caprylic/Capric Triglyceride: Offers similar emollient properties and is derived from coconut oil.
- Isopropyl Myristate: Provides a lightweight, non-greasy feel and enhances skin absorption.
Patents
Isosorbide Dicaprylate is covered by several patents highlighting its applications in cosmetic formulations:
- US9968536B2: Describes compositions comprising isosorbide esters for use in cosmetic and dermatological preparations.
- WO2013017261A1: Details formulations containing isosorbide monoesters and diesters for cosmetic applications.
- US9192552B2: Focuses on personal care compositions utilizing isosorbide diesters to improve the solubility of active ingredients.
References
- Chaudhuri, R. K., & Bojanowski, K. (2017). Improvement of hydration and epidermal barrier function in human skin by a novel compound isosorbide dicaprylate. International Journal of Cosmetic Science, 39(5), 518–526.
- Sytheon Ltd. (2015). Isosorbide Dicaprylate: A Modulator of Biochemical Pathways Linked to Water and Barrier Homeostasis. Cosmetics & Toiletries.
- US9968536B2 - Composition comprising isosorbide esters for cosmetic use.
- WO2013017261A1 - Composition containing isosorbide monoesters and diesters.
- US9192552B2 - Personal care compositions with improved solubility of active ingredients.